Central diabetes insipidus due to lymphocytic infundibuloneurohypophysitis.

نویسندگان

  • H Imai
  • S Okuyama
  • A Komatsuda
  • H Wakui
  • A B Miura
چکیده

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Lymphocytic infundibuloneurohypophysitis: long-term follow-up of a case cured with glucocorticoid.

OBJECTIVE To report a case of infundibuloneurohypophysitis treated with steroid. CLINICAL PRESENTATION A 65-year-old woman who was well until 4 weeks before admission and was not taking any medication presented with acute development of polydipsia and polyuria. Urinary volume was increased to 4,500 ml/day. She showed elevated serum osmolality and low urine osmolality, together with shortage o...

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Rapid exacerbation of lymphocytic infundibuloneurohypophysitis

RATIONALE Lymphocytic hypophysitis is a relatively rare autoimmune disease defined by lymphocytic infiltration to the pituitary. Its rarity and wide spectrum of clinical manifestations make clarification of the pathology difficult. Here, we describe a case we examined from the primary diagnosis to final discharge, showing the serial progression of lymphocytic infundibuloneurohypophysitis (LINH)...

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Evolution of childhood central diabetes insipidus into panhypopituitarism with a large hypothalamic mass: is 'lymphocytic infundibuloneurohypophysitis' in children a different entity?

We report on a 15-year-old girl who had presented with acute onset central diabetes insipidus at the age of 8 years; this was followed by growth failure due to acquired growth hormone deficiency. Initial magnetic resonance imaging showed a uniformly enlarged pituitary stalk and absence of posterior pituitary hyperintensity. Frequent patient examination and magnetic resonance imaging gave unchan...

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Delayed lymphocytic infundibuloneurohypophysitis following successful transsphenoidal treatment of Cushing's disease.

Lymphocytic infundibuloneurohypophysitis is a rare disorder in which neurohypophyseal function is impaired by an autoimmune process. Although several etiologies for this rare entity have been suggested, its occurrence following transsphenoidal adenomectomy has not been reported. A 20-year-old man presented with diabetes insipidus - seven years after successful transsphenoidal microadenomectomy ...

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Serial T1-weighted magnetic resonance imaging changes in a patient with central diabetes insipidus, possibly due to lymphocytic infundibuloneurohypophysitis.

Central diabetes insipidus (CDI), characterized by polydipsia and polyuria due to vasopressin deficiency, is familial, idiopathic or secondary. Idiopathic CDI, which accounts for 10% to 30% of cases of CDI (1), is characterized by selective hypofunction of the hypothalamic–neurohypophysial system. Idiopathic CDI could be an autoimmune disorder (2). Imura et al. (3) studied the processes of idio...

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Infundibuloneurohypophysitis Associated With Sjögren Syndrome Successfully Treated With Mycophenolate Mofetil

Hypophysitis is an inflammatory disorder of the pituitary gland and corticosteroids are usually recommended as the first-line treatment. Hypophysitis related to primary Sjögren syndrome (pSS) is uncommon. We describe the unusual case of a patient with infundibuloneurohypophysitis associated with pSS successfully treated with mycophenolate mofetil (MMF).We describe a case of a 60-year-old man wi...

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عنوان ژورنال:
  • The American journal of medicine

دوره 109 6  شماره 

صفحات  -

تاریخ انتشار 2000